Professor Matthias is a Senior Group Leader at the Friedrich Miescher Institute for Biomedical Research in Basel. He studies the biology of Histone Deacetylases, and his laboratory has made major contributions to understanding the function of several HDACs, including HDAC1, HDAC2 and, notably, HDAC6, for which he published a crystal structure (Nature Chem Biol 2016, 12, 748). Some of his current work has contributed to define the importance of HDAC6 in viral infection and to gain novel structural insights into this enzyme. He received an MSc in Biology from University of Geneva, a PhD in Molecular Biology from University of Heidelberg and an Executive MBA from London Business School. He is an elected member of the Swiss Academy of Natural Sciences.